Soteria® is a library of off-the-shelf excipients that provide proteolytic stabilization to biologics such as monoclonal antibodies and peptides in the small and large intestine lumen and allow uptake of the biologic therapeutic into the gut tissue and systemic absorption.
UTAC® oral delivery platform technology involves a library of bispecific constructs that link the biologic therapeutic cargo to a transporter enzyme and shuttle large macromolecules, such as mAbs, from the intestinal lumen into the bloodstream via the enzyme’s active transport mechanism.
Phloral® is a cutting-edge technology for precise and consistent delivery to the colon. It exploits changes in gastrointestinal pH in combination with the enzymatic activity of the microbiota as independent but complementary release mechanisms to guarantee site-specific release.
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