Licensing and product Development

Spin out from UCL School of Pharmacy based on 20+ years research from laboratory of Prof. Abdul Basit

Experts in oral drug delivery, range of licensable technologies for targeted delivery in GI tract

Unique GI models that provide expert analysis of formulation behaviour under physiologically appropriate conditions

Leadership Team

Dr Maurits Kleijnen

Head of Research

Dr Kleijnen obtained his PhD in Virology from Harvard University. After a postdoctoral research fellowship at Harvard Medical School, he set up his academic research group at Imperial College London as independent Principal Investigator.

After many years at Imperial, Dr Kleijnen moved into biotech roles to lead research groups at Immunocore and 272BIO, with special emphasis on new tech development and capability extension work. Dr Kleijnen sees unique opportunities at Intract Pharma and is passionate about developing transformative new oral biologic therapies for patients with chronic inflammatory and autoimmune diseases.

Vipul Yadav PhD

CEO

Vipul’s research expertise encompasses small molecule and biological drug development, with particular knowledge of overcoming the biological barriers in the gastrointestinal tract to achieve oral administration of biopharmaceuticals. He received his Master of Science degree in Drug Delivery at The School of Pharmacy, University of London, where he researched oral peptide delivery. He then pursued a Ph.D. in Pharmaceutics at the UCL School of Pharmacy, where his research was aimed at exploring the biological mechanisms involved in the oral delivery and intestinal uptake of anti-TNF-α monoclonal antibodies.

Board of Directors

Keith Powell

Chairman

Keith has been in biotechnology since it started and brings many decades of executive experience from various UK and US companies ranging from start-ups to global firms. He worked for GSK and ICI/Zeneca in genetics and molecular biology leading several large groups including Discovery, to finally running Zeneca's patent group. He then joined the West Coast biotech Maxygen, leading the small molecule group through the IPO and growing a business which was spun out as Codexis. On returning to the UK, Keith worked with a fund called BBSF and acted as CEO for several companies in the portfolio, including Spear, sold to Advent International. He led Domainex through a merger with NCE to form a successful business in protein structure-based chemistry. Polytherics was built through organic growth since 2005 to a company of >30 people and is now part of Abzena. Keith is currently chairman of Domainex, and Canbex and has a portfolio of other interests.

Professor Abdul Basit

Founder

Abdul holds the position of Professor of Pharmaceutics at the UCL School of Pharmacy. His research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. Abdul is an international authority on oral drug delivery and absorption, and has published over 300 papers, book chapters, abstracts, and patents. He leads a large multi-disciplinary research group to further the understanding of gastrointestinal physiology by fundamental research. This knowledge has been translated into the design of new technologies and improved disease treatments, many of which are in late stage clinical trials. Abdul has been the recipient of many prestigious awards in his field and is a frequent speaker at international conferences. He also serves as a consultant to numerous pharmaceutical companies, and is on the advisory boards of healthcare organisations, charitable bodies, and scientific journals.

Vipul Yadav PhD

CEO

Vipul’s research expertise encompasses small molecule and biological drug development, with particular knowledge of overcoming the biological barriers in the gastrointestinal tract to achieve oral administration of biopharmaceuticals. He received his Master of Science degree in Drug Delivery at The School of Pharmacy, University of London, where he researched oral peptide delivery. He then pursued a Ph.D. in Pharmaceutics at the UCL School of Pharmacy, where his research was aimed at exploring the biological mechanisms involved in the oral delivery and intestinal uptake of anti-TNF-α monoclonal antibodies.

James Harrison

Non-executive Director

James is the founder and Executive Chairman of Cycle Pharmaceuticals, a young Cambridge-based company focused on improving existing pharmaceuticals. James was formerly CEO of Archimica, an international contract manufacturing organization of active pharmaceutical ingredients and their pre-cursors for the global branded and generic pharmaceutical industries. Archimica has manufacturing sites in the US, UK, Germany, France, and Italy. During his tenure at Archimica, James recruited and led a new management team, and implemented a detailed strategic repositioning of the business. Archimica was sold to the Euticals group in 2011. Prior to Archimica, James was a Managing Director at TowerBrook Capital Partners and a Partner at Soros Private Equity Partners. James began his career working in the mergers and acquisitions department of Morgan Stanley. James holds a first-class MA and MPhil degrees from the University of Cambridge.

Advisory Team

Dr Hiep Huatan, PhD, BPharm (Hons)

CMC

Dr Hiep Huatan is a Pharmaceutical Development Consultant, Managing Director of H2 Pharma Consulting Limited and CEO of a specialty pharmaceutical company, D3 Pharma Limited.  He has over 20-years’ experience in pharmaceutical product development, specialising in the areas of biopharmaceutics, formulation development, process scale-up and regulatory CMC.  Hiep is presently Consultant to several pharmaceutical and medical device companies worldwide. He was previously Chief Development Officer at Diurnal Group plc, Vice-President of R&D at Phoqus Pharmaceuticals, and was Head of Formulation Development at Pfizer Global R&D.  Hiep is a Pharmaceutical Chemist and registered member of the Royal Pharmaceutical Society of Great Britain. He is a leading authority on modified release drug delivery technologies and author of over 50 original publications, including patents, in the field of pharmaceutical formulation, biopharmaceutics, and process design.

Dr Peter Irving

MA MD MRCP

Dr Irving is leading planning and execution of Intract’s clinical development program. Dr Irving trained in Medicine at Cambridge University and The London Hospital Medical College, qualifying with distinction in 1995. He conducted his research at Bart’s and The London on inflammatory bowel disease before moving to Australia for a further period of research. Dr Irving is internationally known as an expert in inflammatory bowel disease (Crohn’s disease and ulcerative colitis) and leads the inflammatory bowel disease service at Guy’s and St Thomas’s Hospital, London where he also runs a large research and clinical trial program. He has previously sat on the IBD Section of the British Society of Gastroenterology and Chaired the Education Committee of the European Crohn’s and Colitis Organization.